Roger L Nation Selected Research

methanesulfonic acid (methanesulfonate)

1/2017	Polymyxin-resistant, carbapenem-resistant Acinetobacter baumannii is eradicated by a triple combination of agents that lack individual activity.
1/2017	Substantial Targeting Advantage Achieved by Pulmonary Administration of Colistin Methanesulfonate in a Large-Animal Model.
1/2015	Polymyxin combinations: pharmacokinetics and pharmacodynamics for rationale use.
1/2014	Pharmacokinetics of colistin methanesulfonate and formed colistin in end-stage renal disease patients receiving continuous ambulatory peritoneal dialysis.
1/2014	Pulmonary and systemic pharmacokinetics of inhaled and intravenous colistin methanesulfonate in cystic fibrosis patients: targeting advantage of inhalational administration.
10/2013	Population pharmacokinetics of colistin methanesulfonate in rats: achieving sustained lung concentrations of colistin for targeting respiratory infections.
11/2012	Pharmacokinetics and pharmacodynamics of 'old' polymyxins: what is new?
10/2011	Dosing of colistin-back to basic PK/PD.
12/2008	In vitro pharmacodynamics of colistin against multidrug-resistant Klebsiella pneumoniae.

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Roger L Nation Research Topics

Disease

76	Infections 10/2022 - 06/2006
22	Critical Illness (Critically Ill) 01/2022 - 12/2007
17	Body Weight (Weight, Body) 01/2021 - 05/2003
6	Cystic Fibrosis (Mucoviscidosis) 10/2019 - 12/2003
4	AIDS-Related Complex (ARC) 01/2021 - 01/2017
4	Acute Kidney Injury (Acute Renal Failure) 03/2019 - 12/2005
3	Gram-Negative Bacterial Infections 01/2018 - 09/2006
3	Chronic Kidney Failure (Chronic Renal Failure) 01/2015 - 10/2004
3	Neoplasms (Cancer) 07/2014 - 06/2003
2	Osteomyelitis 01/2021 - 06/2020
2	Pseudomonas Infections 01/2021 - 10/2012
2	Communicable Diseases (Infectious Diseases) 01/2019 - 09/2006
2	Confusion (Bewilderment) 01/2019 - 02/2015
2	Renal Insufficiency (Renal Failure) 01/2019 - 01/2014
2	Respiratory Tract Infections (Respiratory Tract Infection) 11/2018 - 10/2013
2	Bacteremia 01/2018 - 10/2012
2	Bacterial Infections (Bacterial Infection) 01/2016 - 10/2012
2	Central Nervous System Infections (Central Nervous System Infection) 02/2015 - 07/2006
2	Human Influenza (Influenza) 12/2013 - 04/2013
1	Systemic Inflammatory Response Syndrome (Sepsis Syndrome) 01/2021
1	Sepsis (Septicemia) 01/2021
1	Septic Shock (Toxic Shock Syndrome) 01/2021
1	DNA Repair-Deficiency Disorders (Chromosome Instability Syndromes) 07/2015
1	Aspergillosis 02/2015
1	Pneumonia (Pneumonitis) 02/2015
1	Invasive Pulmonary Aspergillosis 07/2014
1	Chronic Disease (Chronic Diseases) 06/2014
1	Gastrointestinal Diseases (Functional Gastrointestinal Disorders) 06/2014
1	Gram-Positive Bacterial Infections 01/2014
1	Thrombocytopenia (Thrombopenia) 01/2014
1	Liver Diseases (Liver Disease) 01/2014
1	Mycoses (Diseases, Fungus) 07/2013
1	scedosporiosis 09/2012
1	Inflammation (Inflammations) 02/2011
1	Ventilator-Associated Pneumonia 09/2009
1	Cross Infection (Nosocomial Infection) 12/2007
1	Hydrocephalus (Hydrocephaly) 07/2006

Drug/Important Bio-Agent (IBA)

57	Colistin (Coly-Mycin)FDA Link 01/2022 - 05/2003
33	Anti-Bacterial Agents (Antibiotics)IBA 10/2022 - 09/2006
29	Polymyxin B (Aerosporin)FDA LinkGeneric 01/2022 - 12/2007
21	Polymyxins (Polymyxin)IBA 12/2020 - 09/2006
10	Tobramycin (Nebcin)FDA LinkGeneric 01/2022 - 04/2015
9	Meropenem (Merrem)FDA LinkGeneric 01/2021 - 09/2014
9	methanesulfonic acid (methanesulfonate)IBA 01/2017 - 12/2008
8	CreatinineIBA 01/2021 - 08/2013
7	Pharmaceutical PreparationsIBA 10/2022 - 11/2008
5	Carbapenems (Carbapenem Antibiotics)IBA 01/2021 - 01/2018
5	ProdrugsIBA 01/2017 - 10/2011
4	Imipenem FDA Link 01/2018 - 04/2015
3	Ciprofloxacin (Cipro)FDA LinkGeneric 01/2021 - 11/2018
3	Fosfomycin FDA Link 01/2021 - 01/2017
3	Linezolid (Zyvox)FDA Link 01/2014 - 07/2006
2	Piperacillin FDA LinkGeneric 01/2022 - 01/2018
2	Doripenem FDA Link 11/2016 - 05/2015
2	galactomannanIBA 02/2015 - 07/2014
2	LipopeptidesIBA 05/2014 - 08/2010
2	EpitopesIBA 12/2013 - 04/2013
1	Tazobactam Drug Combination Piperacillin (Zosyn)FDA LinkGeneric 01/2022
1	Penicillin G (Benzylpenicillin)FDA LinkGeneric 01/2022
1	Ceftazidime (Fortum)FDA LinkGeneric 01/2021
1	Penicillins (Penicillin)FDA Link 01/2021
1	carbapenemaseIBA 01/2021
1	Dihydrotachysterol (AT 10)IBA 01/2018
1	Methionine (L-Methionine)FDA Link 01/2018
1	PolygelineIBA 12/2017
1	Aztreonam FDA LinkGeneric 01/2017
1	sultamicillin (ampicillin-sulbactam)FDA LinkGeneric 01/2017
1	Amikacin (A.M.K)FDA LinkGeneric 01/2017
1	SodiumIBA 01/2017
1	AS 8IBA 01/2017
1	colistinmethanesulfonic acid (colistimethate sodium)FDA LinkGeneric 01/2017
1	AerosolsIBA 12/2015
1	Metronidazole (Metric)FDA LinkGeneric 06/2014
1	Oxazolidinones (2 Oxazolidone)IBA 01/2014
1	Neutralizing AntibodiesIBA 12/2013
1	Hemagglutinins (Hemagglutinin)IBA 12/2013
1	Membrane Glycoproteins (Membrane Glycoprotein)IBA 12/2013
1	VaccinesIBA 12/2013
1	Antifungal AgentsIBA 07/2013
1	Monoclonal AntibodiesIBA 04/2013
1	Interleukin-6 (Interleukin 6)IBA 10/2012
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 10/2012
1	CytokinesIBA 10/2012
1	Sucrose (Saccharose)IBA 10/2012
1	LipopolysaccharidesIBA 02/2011
1	Protease Inhibitors (Protease Inhibitor)IBA 03/2005

Therapy/Procedure

17	Therapeutics 10/2022 - 12/2009
3	Salvage Therapy 01/2019 - 10/2011
2	Renal Replacement Therapy (Therapies, Renal Replacement) 11/2017 - 01/2017
2	Renal Dialysis (Hemodialysis) 08/2013 - 10/2004
2	Intravenous Administration 11/2008 - 12/2003
1	Debridement 01/2021
1	Respiratory Therapy (Therapy, Respiratory) 01/2019
1	Critical Care (Surgical Intensive Care) 01/2019
1	Urinary Catheters 06/2014
1	Continuous Ambulatory Peritoneal Dialysis (CAPD) 01/2014
1	Length of Stay 09/2012
1	Intraperitoneal Injections 02/2011
1	Ventriculoperitoneal Shunt 07/2006
1	Palliative Care (Palliative Therapy) 02/2006